2-Deoxy-D-glucose CAS No.154-17-6
Chemical Name: 2-Deoxy-D-arabino-hexose
2-deoxy-D-glucose inhibits cell growth.
2-deoxyglucose: an anticancer and antiviral therapeutic.
2-deoxy-D-glucose is a rare and natural monosaccharide that can be made from D-glucose, D-aminoglucose and some amino-polysaccharides. 2-DG exhibits various physiological and pharmacological effects on antivirus, anti-cancer and anti-aging. It has great potential in medicine, foods, and cosmetics, and life science research.
2-deoxy-D-glucose(2-DG) is also called 2-Deoxyglucose, 2-deoxy-D-arabino-hexose or D-arabino-2-deoxyhexose. It is the basic structure of the anticancer drugs such as daunomycin, adriamycin, carminomycins and antibiotics with lactonic ring.
Technical Data
Appearance | White Powder |
M.Wt | 164.16 |
Molecular formula | C6H12O5 |
Solubility | Soluble to 100 mM in water and to 100 mM in DMSO |
Storage | Store at +4°C |
CAS No. | 154-17-6 |
Melting point | 142 to 144 °C (288 to 291 °F) |
2dg glucose, 2 deoxyglucose, 2 deoxy d glucose, 2-deoxy-glucose, 2-deoxy-d-glucose, 2DG has many functions among them:
1. Cancer Treatment: Several US companies are undergoing clinical trials with 2DG for treating cancer.
2. Weight Loss: Its unique property makes it an ideal weight loss management product.
3. Anti - Aging: Aging Research Center- Caloric Restriction in primates and relevance to humans' aging process.
4. Anti - Herpes -: Treatment of AIDS. Washington AIDS Conference, Part III
Glycosylation inhibitors. This paper (TP 23) reported a successful laboratory test of an approach to preventing the (AIDS) virus from initially attaching to the cell, by blocking the expression of glycoproteins on the envelope of the virus. The glycosylation inhibitor used in this test was 2-Deoxy-D-Glucose. The authors, at universities in Philadelphia, Wilmington DE, and Brussels, Belgium, suggested that glycosylation inhibitors might prove useful in treating AIDS.
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